Acceptance strategy

Agree the test conditions before the machine is built.

FAT and SAT become useful when the URS names the package, test product, utilities, runtime, measurements, acceptance values, responsibilities, and evidence to be delivered.

FAT

Factory acceptance

  1. Approved drawings, P&ID, materials, instrument, valve, and software revision check
  2. Specified bag and fitment presentation, opening, fill, recapping, and reject sequence
  3. No-bag/no-fill and loss of the specified temperature, pressure, sterilant, or sterile-gas conditions
  4. Agreed cleaning and pre-sterilization or decontamination sequence, including CIP/SIP where applicable, plus valve states, timers, alarms, reset permissions, and recipe control
  5. Mass or flow measurement against an agreed method and product or substitute medium
  6. Agreed bags/h and kg/h at stated fill mass, viscosity, temperature, handling, and runtime
  7. Batch data, trends, alarm history, audit trail where required, and export format
  8. Guarding, emergency stop, safe recovery, maintenance access, and open-item register
SAT

Site acceptance

  1. Installed P&ID walkdown, utilities, hygienic connections, slopes, drainage, and sterile limits
  2. Upstream sterilizer, sterile hold, filler, conveyor, scale, and downstream interlocks
  3. Actual customer bags, fitments, drums or bins, handling sequence, and filled-package movement
  4. Specified field utilities, including power, air, water, drainage, sterilizing media, and CIP return where applicable, under peak-load conditions
  5. Approved product or test medium at the agreed inlet condition and sustained runtime
  6. On-site execution of the agreed cleaning and pre-sterilization or decontamination sequence, including CIP/SIP where applicable, with records, alarms, deviations, and restart procedure
  7. Operator and maintenance training, spares, manuals, backups, and final document handover
  8. Punch-list closure and responsibility for product/process/packaging validation
Important boundary

Passing FAT or SAT does not by itself prove commercial sterility.

Equipment and automation acceptance must be connected to—but not confused with—the product scheduled process, packaging sterilization, process authority work, microbiological qualification, and routine operating controls required for the intended product and market.